Investigation of Thai Rauwolfia serpentina : analysis and formulation of tablets of the crude drug and extracted reserpine / Sasithorn Wasuwat, Sawat Donsagul

โดย: Wasuwat, Sasithorn
ผู้แต่งร่วม: Donsagul, Sawat | ศศิธร วสุวัติ | Thailand Institute of Scientific and Technological Research
Language: English ชื่อชุด: Res. Proj. No. 17/3 ; Rep. No. 2ข้อมูลการพิมพ์: Bangkok : Thailand Institute of Scientific and Technological Research, 1969 รายละเอียดตัวเล่ม: 17 p.หัวเรื่อง: Medicinal plants | Rauvolfia serpentina | Reserpineสารสนเทศออนไลน์: Click here to access cover สาระสังเขป: Laboratory investigation confirmed that Thai rauwolfia normally sold in the market is Rauwolfia serpentina, some specinons readily meeting pharmaceutical standards. The yield of reserpine+ obtained from the extraction of Thai R. serpentina was improved by selecting the best available procedure and increasing the experimental batch size. A tablet formula of the extracted reserpine proved to be satisfactory over the period of one year aging test. A tablet formula of the crude powdered drug proved to meet the pharmaceutical standards over the period of two year aging test. These findings support the starting of local production of rauwolfia preparations in Thailand and if demand is sufficient could lead to the cultivation of rauwolfia as a special crop. - Authors.
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