Study on antiamoebiasis property, in vitro, of the extracts of Brucea amarissima (Lour.) Merr. (Ratchadat)/ Sasithorn Wasuwat...[et al.]
ผู้แต่งร่วม: Chantarasomboon, Prakongsiri
| Disyaboot, Pornsawan | Nandhasri, Pranee | Ngamwatana, Watana | Tharavanij, Savanat | Wasuwat, Sasithorn
Language: English ชื่อชุด: Res. Proj. no. 17/10 Rep. no. 2ข้อมูลการพิมพ์: Bangkok : TISTR, 1973 รายละเอียดตัวเล่ม: 14 p.หัวเรื่อง: Antiamoebiasis | Brucea amarissima | Ratchadatสารสนเทศออนไลน์: Click here to access full-text สาระสังเขป: Loboratory investigation showed that extracts of the fruits of Brucea amarissima possess antiamoebic property, in vitro, against Entomoeba histolytica. One active fraction at 1.3 mg/ml concentration gave an amoebicidal effect equivalent to that of 0.7-0.8 mg/ml 2-dehydroemetine dihydrochloride injection (Roche). Preliminary study on acute toxicity of the active fraction, on albino mice, was made; it was found that the LD was 184.4 mg/kg body weight (mouse) compared with 59.82 mg/kg (mouse) for 2-dehydroemetine dihydrochloride. Another isolated fraction possesses high toxic property; its LD was 7.1 mg/kg body weight (albino mouse) and its amoebicidal effect at 0.25 mg/ml concentration was equivalent to that of 2-dehydroemetine dihydrochloride at 0.8 mg/ml. Th yield of active fraction was 0.075 per cent, based on dired raw fruits Authors
| ชนิดของทรัพยากร | Location | Call number | สถานะ | Last seen | Copy No. | บาร์โค้ด |
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วว. เทคโนธานี | Available | 2018-08-31 | 1 | RP1973/308 | |
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วว. เทคโนธานี | Available | 2018-08-31 | 2 | RP1973/308-2 |
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